A 23-year-old woman presents with "skipped heartbeats" and on cardiac examination is found to have a midsystolic click followed by a late systolic murmur. Echocardiogram shows prolapse of the mitral valve.Which of the following is true about this condition?
Answer(s): A
Mitral valve prolapse can be diagnosed by auscultation and echocardiogram in as much as 10% of the population. They may be asymptomatic or complain of atypical chest pain, palpitation, shortness of breath, or weakness. An increasing number of complications are being recognized. Although they occur infrequently, they may be life threatening and demand careful evaluation of individuals at risk. Both supraventricular and ventricular arrhythmias occur, as may sudden death. Mitral insufficiency, if present, is usually insignificant but may progress and require valve replacement. There is an increased risk of infective endocarditis. Intraatrial thrombus formation may occur, predisposing to cerebral and peripheral embolism.Because the clot originates in the left atrium, however, pulmonary embolism does not occur more frequently in these patients.
A 19-year-old high school senior complains of feeling "fat and ugly" despite being extremely thin. She takes small amounts of food at meals and occasionally gags herself to induce vomiting after meals. Which of the following is commonly associated with this disorder?
Answer(s): D
The history of severe, self-induced weight loss with an abnormal attitude toward food, weight, and body image in an adolescent female strongly suggests anorexia nervosa. Common symptoms are amenorrhea, not menorrhagia or metrorrhagia, constipation, and cold intolerance. Examination frequently reveals cachexia, hypothermia, bradycardia, hypotension, percarotenemic skin, and increased lanugo-like body hair. Decreased thyroid and pituitary function are evident on laboratory tests, but thrombocytopenia and anemia are not common
A 59-year-old woman had a left modified radical mastectomy for intraductal carcinoma 2 years previously. She presents with confusion, lethargy, and thigh pain. X-rays reveal a lytic lesion in the shaft of the femur.Which of the following blood abnormalities is most likely?
Hypercalcemia is a common complication of malignancy. Mechanisms include bone metastases, humoral secretion (e.g., osteoclast-activating factor), prostaglandin, or ectopic parathormone production and immobilization. Hypercalcemia is often manifested by confusion and lethargy. The other metabolic abnormalities usually are not associated with confusion. Therapy is directed at increasing renal calcium clearance and inhibiting further bone resorption. Saline infusion raises the glomerular filtration rate and decreases calcium reabsorption in the proximal tubule. Under life-threatening circumstances, the infusion may need to be aggressive, as much as 6 L of saline daily plus furosemide. Radiotherapy will do nothing for the calcium. Tamoxifen is an antiestrogen used in the treatment of breast carcinoma and other malignancies. When used in the presence of bone metastases, it may contribute to hypercalcemia.Chemotherapy will not decrease the calcium levels. Glucocorticoids have an antitumor effect and reduce tumor production of humoral mediators, but act slowly.
A 59-year-old woman had a left modified radical mastectomy for intraductal carcinoma 2 years previously. She presents with confusion, lethargy, and thigh pain. X-rays reveal a lytic lesion in the shaft of the femur.Which of the following is the most appropriate initial therapy?
Answer(s): B
A55-year-old retired policeman has had hypertension for about 15 years for which he takes hydralazine. He has a 35 pack-year tobacco history and continues to smoke one pack a day. On his visit, he complains about the appearance of his nose and asks if something can be done to decrease the redness.Which of the following statements is correct?
Answer(s): C
He should avoid alcohol and spicy foods because these along with the heat, emotional stress, and hot temperature foods can aggravate rosacea. Hydralazine is a vasodilator and could worsen his nasal erythema. Smoking vasoconstricts rather than dilates blood vessels. Metronidazole gel is an effective topical therapy. Laser therapy is usually done after the other interventions have been tried
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answer to this question "what administrative safeguards should be implemented to protect the collected data while in use by manasa and her product management team? " it should be (c) for the following reasons: this administrative safeguard involves controlling access to collected data by ensuring that only individuals who need the data for their job responsibilities have access to it. this helps minimize the risk of unauthorized access and potential misuse of sensitive information. while other options such as (a) documenting data flows and (b) conducting a privacy impact assessment (pia) are important steps in data protection, implementing a "need to know" access policy directly addresses the issue of protecting data while in use by limiting access to those who require it for legitimate purposes. (d) is not directly related to safeguarding data during use; it focuses on data transfers and location.
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